alternative to our lifestyle as it states, these help ‘supplement’ our current diets and lifestyles. There are supplements that can assist in increasing insulin sensitivity, including cinnamon (Medagama, 2015), chromium (Anderson, Cheng, Bryden, Polansky, Cheng, Chi & Feng, 1997), magnesium (Mooren, Gruger, Volker, Golf, Wadepuhl, & Kraus, 2011), and berberine (Pang, Zhau, Zhou, Zhao, Wang, Gu & Tong, 2015). Prevention is key as one approaches the middle and later ages. Recommend patients to act and get screened for their blood sugar levels. HbA1c is a better indicator of the blood sugar levels and potentially insulin tolerance tests as well. Even if medications are not indi-cated despite a borderline HbA1c, there are many things to start on that can prevent and optimize blood sugar levels and insulin sensitivity. By doing so, not only would it be supportive of your pa-tient’s risk of cardiovascular disease, but also reduce the risk of developing Alzheimer’s dementia. References Adam, T. C., Hasson, R. E., Ventura, E. E., Toledo-Corral, C., Le, K. A., Mahurkar, S., Lane, C. J., Weigensberg, M. J., & Goran, M. I. (2010). Cortisol is negatively associated with insulin sensitiv-ity in overweight Latino youth. The Journal of clinical endocri-nology and metabolism, 95(10), 4729–4735. https://doi. org/10.1210/jc.2010-0322 Alzheimer’s Association. (2020). 2020 Alzheimer’s disease facts and figures. Retrieved from: https://doi.org/10.1002/ alz.12068 Anderson, R. A., Cheng, N., Bryden, N. A., Polansky, M. M., Cheng, N., Chi, J., & Feng, J. (1997). Elevated intakes of supplemental chromium improve glucose and insulin variables in individuals with type 2 diabetes. Diabetes, 46(11), 1786–1791. https:// doi.org/10.2337/diab.46.11.1786 Bird, S. R., & Hawley, J. A. (2017). Update on the effects of physical activity on insulin sensitivity in humans. BMJ open sport & exercise medicine, 2(1), e000143. https://doi.org/10.1136/ bmjsem-2016-000143 Bredesen D. E. (2014). Reversal of cognitive decline: a novel therapeutic program. Aging, 6(9), 707–717. https://doi. org/10.18632/aging.100690 Campbell, J. M., Stephenson, M. D., de Courten, B., Chapman, I., Bellman, S. M., & Aromataris, E. (2018). Metformin Use Associ-ated with Reduced Risk of Dementia in Patients with Diabetes: A Systematic Review and Meta-Analysis. Journal of Alzheimer’s disease : JAD, 65(4), 1225–1236. https://doi.org/10.3233/ JAD-180263 de la Monte, S. M., & Wands, J. R. (2008). Alzheimer’s disease is type 3 diabetes-evidence reviewed. Journal of diabetes sci-ence and technology, 2(6), 1101–1113. https://doi. org/10.1177/193229680800200619 Donga E, van Dijk M, van Dijk JG, et al. A single night of partial sleep deprivation induces insulin resistance in multiple metabolic pathways in healthy subjects. J Clin Endocrinol Metab. 2010;95(6):2963-2968. doi:10.1210/jc.2009-2430 Kim, Y. A., Keogh, J. B., & Clifton, P. M. (2018). Probiotics, preb-iotics, synbiotics and insulin sensitivity. Nutrition research re-views, 31(1), 35–51. https://doi.org/10.1017/ S095442241700018X Kurochkin, I. V., Guarnera, E., & Berezovsky, I. N. (2018). Insu-lin-Degrading Enzyme in the Fight against Alzheimer’s Disease. Trends in pharmacological sciences, 39(1), 49–58. https://doi. org/10.1016/j.tips.2017.10.008 Medagama A. B. (2015). The glycaemic outcomes of cinnamon, a review of the experimental evidence and clinical trials. Nutrition journal, 14, 108. https://doi.org/10.1186/s12937-015-0098-9 Mooren, F. C., Krüger, K., Völker, K., Golf, S. W., Wadepuhl, M., & Kraus, A. (2011). Oral magnesium supplementation reduces insulin resistance in non-diabetic subjects -a double-blind, placebo-controlled, randomized trial. Diabetes, obesity & me-tabolism, 13(3), 281–284. https://doi.org/10.1111/j.1463-1326.2010.01332.x Naderpoor, N., Mousa, A., Gomez-Arango, L. F., Barrett, H. L., Dekker Nitert, M., & de Courten, B. (2019). Faecal Microbiota Are Related to Insulin Sensitivity and Secretion in Overweight or Obese Adults. Journal of clinical medicine, 8(4), 452. https:// doi.org/10.3390/jcm8040452 Pang, B., Zhao, L. H., Zhou, Q., Zhao, T. Y., Wang, H., Gu, C. J., & Tong, X. L. (2015). Application of berberine on treating type 2 diabetes mellitus. International journal of endocrinology, 2015, 905749. https://doi.org/10.1155/2015/905749 Song, E.S., Rodgers, D.W. & Hersh, L.B. (2018). Insulin-degrad-ing enzyme is not secreted from cultured cells. Sci Rep, 8, 2335. https://doi.org/10.1038/s41598-018-20597-6 www.Cndoctor.ca CND_Contemporary Medical _Oct20_CSA.indd 1 October 2020 Chiropractic and Naturopathic Doctor 15 2020-09-18 1:22 PM