it may involve “up regulatory” and “down regulatory” mechanisms on the nociceptive pathways, including phe-nomena such as peripheral and central sensitization, silent nociception, and neuronal plasticity. Also related to the neurophysiology of inflammation, sym-pathetic nervous system hyperactivity is known to be a majorcontributor to all pain problems. Less understood contributors in-clude dysfunction of pre-and post-gan-glionic sympathetic neurons, abnormal visceral autonomic activity, lack of sufficient non-noxious information from these or adjacent segments re-lated to the kinetic chain (proximal and distal joints, synergistic and/or antago-nistic muscles, etc.). It is even possible that any nociceptive signal from any innervated tissue, regardless of topo-graphic location, could become a source of amplification in a given pain problem. Practitioners of pain medicine need to be able to evaluate and identify these common contributors to pain syn-dromes. Being able to provide a timely, relevant treatment to optimize func-tional recovery requires a systematic, yet holistic approach. A practical neu-rofunctional treatment model (See: “The neurofunctional era: Optimizing the use of therapeutic resources” on Canadianchiropractor.ca) will be best to help practitioners select the most appropriate neuromodulatory inter-ventions for the most relevant levels involved in each pain problem. For the sake of making this discus-sion as clinically relevant as possible, a hypothetical elbow pain problem has been selected to illustrate the discus-sion, and an accompanying diagram (page 26) has been provided to reflect the 10 kinds of contributors to the pain experience, visually. Discussion of each contributor is signalled with the same number used in the diagram. 1. Local contributors: nociceptive fibres with receptor fields on der-matomal, myotomal, and scleroto-mal tissues Nociception is a neurological seg-mental phenomenon related to periph-eral nervous system and spinal cord activity. Nociceptive signals are gener-ated in response to chemical, mechan-ical and thermal stimuli acting over free nerve endings (belonging to C fibres and A-delta fibres) located on dermat-omal, myotomal or sclerotomal struc-tures. These C and A-delta fibers are func-tionally referred to as nociceptive fib-ers, because of their ability to inform the central nervous system (CNS) about noxious stimuli, i.e. potentially harmful or unpleasant stimuli, whether there has been already tissue damage or not. These are the only nerve fibers capable of detecting noxious activity in the tissues, and to convey it to the CNS. These nociceptive signals are Study Proves that Bone Enlarges with Injury Researchers at the University of Cal-ifornia have discovered a mechanism within bone that causes its shape to change when injured 1 . This can affect osseous integrity, joint function and soft tissue tension, resulting in pain, in-stability, joint degeneration, organ dys function, and many of the neurological effects of TBI (concussion), due to cra-nial bone deformity. Based on this new evidence, as chiro-practors, we need to address these actual changes in bone structure, in order to fully restore function. For example, if the femoral head is enlarged, the hip joint will become in-flamed and painful, leading to degener-ation and the possible need for surgery. Matrix Repatterning is a gentle, evi-dence-based assessment and treatment system, which can restore normal bone structure within a few minutes, allow-ing many hip, knee, shoulder and spinal surgeries to be avoided. Normalize bone structure to deliver breakthrough results for your toughest patients will allow your patients to move on from their limiting conditions and enjoy life without pain. “Matrix Repatterning has changed my life and my career. It is the most pow-erful clinical approach I have ever come across, and I will never go back to the old way of doing things.” “This procedure can be very helpful for… TBI and other head injuries, even as a first intervention. Observing such cases has led me to hope that one day Measureable Change in Bone Size Matrix Repatterning will be routinely These remarkable results are lasting applied in hospital emergency depart-and dramatic, and have been verified by ments.” independent radiologists, researchers, Dr. Norman Doidge, MD Author: The Brain That and clinicians. This treatment system Changes Itself & The Brain's Way of Healing Dr. Andy Stella, DC, CMRP, Minneapolis, MN Visit MatrixForPractitioners.com for information and free educational webinar 1-877-905-7684 1.Fantner GE, Hassenkam T, Kindt JH, Weaver JC, Birkedal H, Pechenik L, Cutroni JA, Cidade GA, Stucky GD, Morse DE, Hansma PK , sacrificial bonds and hidden length dissipate energy as mineralized fibrils separate during bone fracture, Nat Mater. 2005 Aug;4(8):612-6. Epub 2005 Jul 17. www.canadianchiropractor.ca CC_Matrix_April19_CSA.indd 1 April 2019 Canadian Chiropractor 25 2019-03-06 8:59 AM