Kaprex ® Targeted Joint Relief. * Want to offer your patients an effective, safer way to target joint relief? Then recommend Kaprex. Cell proteomic research, safety evaluations, human ex vivo research, and clinical studies suggest Kaprex provides effective relief of minor pain—without serious adverse effects.*1-3 • Shown to be comparable in PGE2 modulation to a leading conventional approach, with a high degree of predicted safety for the heart, kidneys, GI tract, and liver* • Modulates PGE2 activity in vitro more effectively than many natural competitive ingredients* Give your patients worry-free joint relief—order Kaprex today!* East Coast 800.638.2848, Chicago 874.438.9420, Canada 800.268.6200 all other areas 800.692.9400 1. Desai A,Konda VR, Hall A, Bland J, Tripp M. Comparison of anti-inflammatory activity of two selective kinase response modulators (SKRMs), rho-iso-alpha acids (RIAA) and tetrahydro-iso-alpha acids (THIAA), in lipopolysaccharide (LPS) mediated inflammation in RAW 264.7 macrophages. The FASEB Journal . 2007;21:702. 2. Lerman RH, Liska D, Tripp M, et al. Summary of effects of a reduced iso-alpha acid (RIAA) rosemary extract, and oleanic acid supplement on parameters of cardiovascular health. Proprietary Clinical Research Report. Gig Harbor, WA: Functional Medicine Research Center;2004. 3. Minich DH, Bland JS, Katke J, et al. Clinical safety and efficacy of NG440: a novel combination of rho iso-alpha acids from hops, rosemary, and oleanolic acid for inflammatory conditions. Can. J. Physiol. Pharmacol. 2007;85:872-883. †U.S. Patent nos. 7,195,785; 7,205,151. * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, or prevent any disease. © 2008 Metagenics, Inc.