While safe for all ages, the dosage will vary based on age. Ketones naturally act as a diuretic, so you lose salt, potassium, calcium and magnesium. It is generally encouraged to increase sodium intake with ketones. Ketosis is not diabetic ketoacidosis, which is a serious complication of un-controlled diabetes when the body produces high levels of blood acids, called ketones, in conjunction with high levels of glucose. Diabetic patients should only use exogenous ketone sup-plements under the care of a physician. Taking the recommended dose of exog-enous ketones puts the body into safe, therapeutic ketosis. However, theoreti-cally, it could be possible to elevate your blood ketones to a dangerous level with exogenous ketones. A person would have to consume an exorbitant amount to elevate blood ketones; that is if the water-soluble ketones are all absorbed. This would be about 20 servings of the current consumer-based products. QUALITY MATTERS As we all know, it’s quality over quantity. It is not about the amount of BHB in the product but rather the bioavailabil-ity. Although the product choices are limited at this point, the product you choose should be most bioavailable for the greatest clinical impact and thera-peutic effect. Ketone supplementation essentially substitutes for ketogenesis, but only bioavailability of ketones in the blood for cellular use creates ketosis. Therefore, it is the quantity in the blood stream that is important, not the quan-tity ingested. Quality studies are being conducted at the moment. With research emerg-ing, it is up to health-care practition-ers to stay informed on this topic. With the effects of ketone bodies, implications can span across so many conditions we see in the clinical set-ting. The exogenous ketones’ ability to affect mild subjective complaints – such as brain fog, cognitive decline and low energy to conditions such as neurological disorders, autoimmune disorders, diabetes and acute and chronic musculoskeletal conditions – make the research being conducted at the moment applicable to our chiro-practic practices. Research continues to emerge reg-ularly to help us better understand the science and use of exogenous ketones. (Editor’s note: For a list of references cited for this article, email the editor at [email protected].) APPLICATIONS RESEARCH LIMITATIONS There are limitations to the current research on ketones. Some evidence available are based on case studies and others that use rat subjects. Some thoughts are proven while others are preliminary or speculation. However, they all provide a foundation and groundwork for future studies. OsteOpathy fOr the Over 50s MaINtaINING fUNCtION aND treatING DysfUNCtION This book is intended to provide a study of the biomechanics and physiology of somatic dysfunction as it relates to individuals over the age of 50. Practitioners require information about the diagnosis of somatic dysfunction and application of osteopathic manipulative treatment specifically as it relates to this age group – and this is where this book is invaluable. The main body of the text considers the relevance of somatic function and dysfunction in multiple clinical areas including cardiology, pulmonology, gastroenterology, urology, neurology and rheumatology. The diagnostic approach to the patient over the age of 50 and osteopathic manipulative treatment is thoroughly described. This book provides information on the biomechanics and physiology of somatic dysfunction for the osteopathic treatment of older adults in a thorough, yet easy to approach fashion. 24 Canadian Chiropractor June 2017 CC_book ad_JulyAug16_MLD.indd 1 www.canadianchiropractor.ca 2016-06-21 7:45 AM
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